terça-feira, abril 11, 2006
"DIRECT EVOLUTION OF A FULL PROFESSOR"
Recebi isto por mail e achei que deveria partilhar convosco. Quem é cientista e está a fazer o PhD vai achar este artigo uma grande verdade. Além de que se pode rever os orientadores no outcome final eh eh eh
Eu só digo que saí para a industria...
"DIRECT EVOLUTION OF A FULL PROFESSOR"
(author unknown)
ABSTRACT:
Success in academia is hypothesized to require specific phenotypes. Inorder to understand how such unusual traits arise, we used human clones toidentify the molecular events that occur during the transition from a graduatestudent to professor.A pool of graduate student clones was subjected to several rounds ofrandom mutagenesis followed by selection on minimal money media in the absenceof dental insurance. Students surviving this selection were further screenedfor the ability to work long hours with vending machine snacks as a solecarbon source; clones satisfying these requirements were dubbed "post-docs".In order to identify assistant professors from amongst the post-docs,this pool was further mutagenized, and screened for the ability to turnesoteric results into a 50 minute seminar. Finally, these assistant professorswere evaluated for their potential to become full professors in two ways:first, they were screened for overproduction and surface display of stressproteins such as Hsp70. Assistant professors that displayed such proteins (so-called "stressed-out" mutants) were then fused to the M13 coat protein,displayed on phages and passed over a friend and family members column,to identify those that were incapable of functional interactions. These werecalled full professors.
Although these mutants arose independently, they shared striking phenotypes.These included the propensity to talk incessantly about their ownresearch, the inability to accurately judge the time required to complete benchwork, and the belief that all their ideas constituted good thesis projects. Thelinkage of all these traits suggests that these phenotypes areco-ordinately regulated. Preliminary experiments have identified a putative global regulator. Studies are currently being conducted to determine ifover-expression of this gene product in post-docs and grad students canspeed up the grad student-full professor evolutionary process.
Although these mutants arose independently, they shared striking phenotypes.These included the propensity to talk incessantly about their ownresearch, the inability to accurately judge the time required to complete benchwork, and the belief that all their ideas constituted good thesis projects. Thelinkage of all these traits suggests that these phenotypes areco-ordinately regulated. Preliminary experiments have identified a putative global regulator. Studies are currently being conducted to determine ifover-expression of this gene product in post-docs and grad students canspeed up the grad student-full professor evolutionary process.
EDITORS COMMENTARY:
The present paper, titled "Direct Evolution of a Full Professor" is afascinating document, well worth publication. However, the authors failto note several topics sure to be of interest to the Journal's readers. Forexample, it is a well-documented phenomenon that transition to industrycan occur at any point along the evolutionary pathway. The authors fail tocomment on the possible mechanisms behind such versatility. Plasmid-borneresistance genes encoding a tropism for rich media have been postulated to fulfil this function.
In support of this hypothesis, it may be noted that previousresearchers who attempted to isolate this plasmid quickly underwent transition and never published their findings.
Comments:
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Vais-me desculpar mas n vou ler isto... parece-me cientifico demais para a minha cabeça! Não se arranja por aí um textito qualquer do Shakespeare ou assim?? :P
acho que nunca vou ser a full professor... even if I also have the inability to accurately judge time required for complete benchwork....mas acho nao faz mal, nao e' tiagino :)?
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: abril 18, 2006 7:55 da manhã
: abril 18, 2006 7:55 da manhã << Home
